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BIOPROSP_19

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Day 1 - 25 February

Parallel sessions

09:00 - 12:00

Pre-seminar. "Marine biotech entrepreneurship: Capturing the value of scientific results"

Organized by eCoast, Macro Cascade and UiT. See information at the "pre-conference" tab above.

Pre-workshop: Marine proteins - latest news on enzymatic hydrolysis

Developed by NORCE Research and Biotech North. See information at the "pre-conference" tab above.

12:00 - 13:00

Lunch

Opening session

13:00 - 13:30

Accelerating the BlueBio Sector: Snapshots of a story written by the XV century discoveries country!

In this presentation Helena will give an overview of the European Blue bioeconomy sector and illustrate how Portugal is fostering development of the blue bioeconomy via acceleration of blue biobased entrepreneurs and scientists

13:30 - 14:00

Value creation based on polymers from marine algae

An industry perspective on how polymers currently extracted from marine algae can be used in new ways, and opportunities created through new seaweed derived biomolecules

14:00 - 14:15

Coffee

Session 1 - Biorefinery for Marine Resources

(including micro algae, macro algae, by products from fisheries)

    This session is sponsored by NORCE - The Norwegian Research Centre AS

14:15 - 15:00

Key note: Biorefinery of brown macro algae for high value added products

15:00 - 15:30

Biorefinery and exploitation of seaweed from the coast of Norway

  • Status, challenges and perspectives for seaweed harvesting and cultivation in Norway
  • Development of the toolbox for seaweed biorefineries
  • Innovations based on seaweed based biopolymers

16:00 - 16:10

Elucidating lipid accumulation and DHA synthesis

In Aurantiochytrium sp by transcriptome, proteome and metabolome analyses

Inga Marie Aasen, Researcher, SINTEF (Norway)

16:10 - 16:20

Engineering the sensory quality of marine ingredients using "marine sensory enzymes"

Marianne Goris, Resaearcher, NORCE (Norway)

16:20 - 16:30

Algae-to-Market Lab Ideas

A Blue Lab for fast Bioproduct Development from Invasive Seaweeds

Rafael Félix, Researcher, Instituto Politécnico de Leiria (Portugal)

16:30 - 17:15

Visits at the posters and the sponsor exhibitions

  • Build network among the industry representatives
  • See exciting research results from all over the world - there are more than 80 posters
  • Coffee, beverages and fruit

End of day 1

The bus leaves at 17:20

19:30

Opening party

Day 2 - 26 February

Session 2 - Synthethic biology

(including design and construction of new biochemical entities such as marine organisms and/or their pathways and/or their enzymes)

09:00 - 09:30

Keynote: Microbial synthetic biology for biosynthesis of products and materials

  • Design principles for engineering yeast to produce and sense therapeutic molecules
  • Engineering yeast at the genome level to make specialist strains
  • Using microbial consortia to grow functionalised biomaterials

09:30 - 10:00

Keynote: Genome editing as a promising approach to redesign microalgae metabolism

  • Introduction on genome editing for microalgae strains development
  • Outcomes for basic and applied research
  • Generation of multiple gene knock-out strains using CRISPR/Cas9 ribonucleoproteins

10:00 - 10:15

Strain optimization of diatoms using the CRISPR/Cas9 technology

  • CRISPR/Cas9 genome editing of diatoms enables strain optimization for biotechnological applications.
  • The “light-to-biomass” energy conversion efficiency defines overall production costs of commercially interesting compounds from diatom mass cultures.
  • Creation of strains with truncated light harvesting antennas can increase light penetration through the mass culture and improve productivity.

10:15 - 10:35

Unlocking the potential of synthetic biology to produce complex natural products

  • Over 20% of all FDA-approved new chemical entities are based on natural products
  • The commercial production of natural products is often challenging due to complex chemistries and a limited culturability of the natural producer organisms
  • Synthetic biology is an attractive option to combine the capacity of nature to produce complex molecules with organisms that can be grown at large scale

10:35 - 11:00

Coffee break

11:00 - 11:10

The MarSynth project – Marine DNA modifying enzymes for synthetic biology

Yvonne Piotrowski, researcher, Department of Chemistry, UiT (Norway)

11:10 - 11:20

Translocation and secretion of recombinant proteins -

In a novel cold-adapted bacterial expression host

Jenny Johansson Söderberg, researcher, UiT (Norway)

11:20 - 11:30

Genome engineering of Bacillus subtilis using CRISPR/Cas9

Antonio Garcia-Moyano, researcher, NORCE (Norway)

11:30 - 12:00

Mini-session: Responsible Research and Innovation

  • Responsible research and innovation (RRI) brings diverse groups of people together to think through, reflect on, and assess the potential implications of developing science and technology.
  • Benefits of incorporating RRI aspirations and practices include enhancing relevance and legitimacy of, as well as societal preparedness for scientific and technological pursuits.
  • This session will share practical ways to integrate RRI thinking and activities into cutting-edge study of biomolecules from marine environments for society.

12:00 - 13:00

Lunch

Session 3 - Marine Bioactive Molecules

(for various applications, in medicine, pharmaceutical, nutraceutical, cosmeceutical industries and more)

13:00 - 13:45

Key note: Marine Microbiome as a Source of Anticancer Compounds

State of the art in marine biotechnology is being applied to drug discovery under the experience of PharmaMar, a spanish company focused in research, development and commercialization of marine derived drugs for the treatment of cancer.

  • The cases of pederin, ecteinascidins (trabectedin, Yondelis©) or didemnins are examples of the role of marine microbiome as producers of bioactive metabolites with application in oncology
  • Genomic mining for polyketide synthases (PKS) and non ribosomal peptide synthetases (NRPS) improves the probability of success in drug discovery using marine microorganisms, both in isolated genomes and metagenomes

13:45 - 14:15

Computational genome mining tools for the discovery of bacterial natural products

Prof. Nadine Ziemert will introduce computational tools developed by the Ziemert lab to help prioritise bacterial strains with novel natural products and biosynthetic gene clusters that encode antibiotics.

14:15 - 14:45

The medicinal power of marine teleost oocytes: From discovery to treatment

  • Lipids of life
  • Targeting auto-immune disease
  • Psorax35: A successful double blind placebo controlled study targeting Psoriasis vulgaris

14:45 - 15:00

Coffee break

15:00 - 15:10

Evaluation of the anti-fouling potential of the cyanobacterial metabolites portoamides

Using a multi-bioassay approach

Jorge Antunes, PhD-student, CIIMAR/University of Porto (Portugal)

15:10 - 15:20

Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi

Espen Hansen, professor, UiT (Norway)

15:20 - 15:30

Screening of new sustainable marine microbial sources of omega-3 fatty acids from coastal seawater

Mónica Estupiñán Romero, researcher, AZTI-Tecnalia (Spain)

15:30 - 16:15

Visit at the posters and the sponsor exhibitions

  • Build network among the industry representatives
  • See exciting research results from all over the world - there are more than 80 posters
  • Coffee, beverages and fruit

End of day 2

The bus leaves at 16:30

19:00

Conference dinner

Day 3 - 27 February

Session 4 - New resources and trends in marine biotech

Emerging Tools / Discovery Techniques

09:00 - 09:45

Key note: Consumers and markets for marine ingredients and products

  • Great shifts are occuring with consumers and markets are evolving faster than ever
  • How do marine biotech products fit into the changing consumer and market landscape
  • What are the hurdles and opportunities to bring these products to the market and make them stand out

09:45 - 10:30

Key note: Connecting Genes to Molecules with Isotope Labeling Mass Spectrometry: A Systems Approach

  • Although genome mining can now identify many classes of biosynthetic genes, predicting the precise structures of the products of these gene clusters remains challenging
  • Using a combination of isotope labeling and high-resolution mass spectrometry we have developed a new platform to link natural products to their cognate gene clusters
  • This new platform can be used to identify all products from a given gene cluster, or all natural products biosynthesized by a given organism for universal natural products characterization

10:30 - 11:00

Biorefining and Processing of Marine Biomaterial for Food and Feed

An overview of the existing possibilities

11:00 - 11:15

Coffee break

11:15 - 11:25

Challenges and Optimal Business Strategies in Marine Bio-Resource Organisations

Jane Eva Collins, Science and Policy Research Fellow, ABS-int & KU Leuven (Belgium)

11:25 - 11:35

Use of herring milt hydrolysate for the improvement of the metabolic syndrome

In vitro and in vivo experiments

Rachel Durand, PhD-student, Université Laval (Canada)

11:35 - 11:45

Bioactivity mapping of an in-line SPE fractionated Fucus vesiculosus extract

Using LC-MS/MS based metabolomics

Larissa Buedenbender, researcher, GEOMAR (Germany)

Closing Session

Closing remarks

Ceremony: Prize for the best poster at BIOPROSP_19

12:00

Lunch

End of BIOPROSP_19

The bus leaves at 12:45